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PRECLINICAL MODELS Our approach to understanding the processes mediating the addictive effects of drugs requires the use of many different behavioral tasks. This multi-task approach is necessitated by the complex action of drugs in the central nervous system (CNS). From our perspective, one way to understand this complex action is to take advantage of different tasks that have been developed to understand different components of a drug's action. For example, self-administration is well suited to measure the reinforcing effects of a drug, whereas conditioned taste avoidance measures the aversive- or avoidance-inducing effects. Although some of our research uses these tasks as mere assays, you will notice that much of our research is designed to understand the functional relations (behavioral and neuropharmacological) that affect what is being learned.
Last updated: 11-07-06
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