Developing biosensor systems has long been a high priority for NASA because they are essential for monitoring health and safety of the astronaut. However, continuous, reliable, long-term, ambulatory, biostatistical monitoring that does not interfere with the missions' sometimes physically rigorous duties is still elusive. We therefore are creating a new critical biosensing technology that will make NASA’s crewed space exploration missions more capable. The aim of our work is to create a new biosensing system that is intuitive and transparent to the biological host yet robust and reliable. The new biostatistical sensing system is designed to facilitate monitoring the health of astronauts on long-term missions where terrestrial medical facilities and personnel are inaccessible.