Pawel Ciborowski,
PhD
Assistant Professor
University of Nebraska Medical Center
Dept. of Pharmacology
985800 Nebraska Medical Center DRC #3048
Omaha, NE 68198-5800
(402) 559-3733
fax: (402) 559-7495
pciborowski@unmc.edu
SELECTED PUBLICATIONS IN REFEREED JOURNALS (From 37 publications):
E. M. Hiltbold, M. D. Alter, P. Ciborowski and O. J. Finn. Presentation
of MUC1 tumor antigen by class I MHC and CTL function correlate with
the glycosylation state of the protein taken up by dendritic cells.
Cellular Immunology 1999, 194:143-149.
P. Ciborowski and O.J.Finn. Expression of MUC-1 mucin in insect
cells using baculovirus vectors. In: Glycoproteins Methods and Protocols,
The Mucins; Methods in Molecular Biology, v. 125, (Tony Corfield
ed.) 2000, Humana Press, Totowa, NJ, pp. 471-486.
E. M. Hiltbold, A. M. Vlad, P. Ciborowski, Simon C. Watkins, and
O. J. Finn. Mechanism of unresponsiveness to circulating antigen
MUC1 is a block in intracellular sorting and processing by dendritic
cells. J. Immunol. 2000, 165:3730-3741.
P. Beatty, F-G. Hanisch, D. Beer Stolz, O.J. Finn, and P. Ciborowski.
Biochemical characterization of the soluble form of tumor antigen
MUC1 isolated from sera and ascites fluid of breast and pancreatic
cancer patients. Clin. Canc. Res. 2001, 7:781s-787s.
H. Kao, A. A. Amoscato, P. Ciborowski, and O. J. Finn. A new strategy
for tumor antigen discovery on in vitro priming of naïve T cells
with dendritic cells. Clin. Canc. Res. 2001, 7:773s-780s.
M. Soares, F-G. Hanisch, O.J.Finn, and P. Ciborowski. Recombinant
human tumor antigen MUC1 expressed in insect cells: structure and
immunogenicity. Prot. Expr. Purif. 2001, 22:92-100.
P. Ciborowski and O.J. Finn. Non-glycosylated tandem repeats of
MUC1 facilitate attachment of breast tumor cells to normal human
lung tissue and immobilized extracellular matrix proteins (ECM) in
vitro: potential role in metastasis. Clin & Exp. Metastasis 2002,
19:339-345.
K.A. Carlson, P. Ciborowski, C. Schellpeper, T. M. Biskup, R.F.
Shen, X. Luo, C. J. Destache, and H.E. Gendelman, Proteomic fingerprinting
of HIV-1-infected human monocyte-derived macrophages: A preliminary
report. J. Neuroimmunol. 2004, 147:35-42.
P. Ciborowski, Y. Enose, A. Mack, M. Fladseth, and H. Gendelman.
Diminished matrix metalloproteinase 9 secretion in human immunodeficiency
virus infected mononuclear phagocytes: modulation of innate immunity
and implications for neurological disease. J. Neuroimmunol. 2004,
157:11-16.
Y. Enose, C. Destache, A. Mack, J. Anderson, F. Ullrich, P. Ciborowski,
and H. Gendelman. Proteomic Fingerprints Distinguish Microglia, Bone
Marrow and Spleen Macrophage Populations. Glia. 2005,
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