|
|
James Van Etten, PhD
Publications and Research Interests:
From 1964 to present: 163 research papers and 29 reviews. Of the
research papers, 14 deal with the isolation and characterization
of the unusual bacteriophage phi 6 and 103 deal with the isolation
and characterization of chlorella viruses. The majority of the remaining
papers are on the physiology and biochemistry of fungal development.
All of my current research efforts are on viruses of eukaryotic algae.
Publications: since 2000
Sun, L, Y. Li, A.K. McCullough, T.G. Wood, R.S. Lloyd, B. Adams,
J.R. Gurnon, and J.L. Van Etten. (2000). Intron conservation in a
UV-specific DNA repair gene encoded by chlorella viruses. J. Mol.
Evol. 50:82-92.
Yan, X., N.H. Olson, J.L. Van Etten, M. Bergoin, M.G. Rossmann,
T.S. Baker. (2000). Structure and assembly of large, lipid-containing
dsDNA viruses. Nature Structural Biology 7:101-103.
Lavrukhin, O.V., J.M. Fortune, T.G. Wood, D.E. Burbank, J.L. Van
Etten, N. Osheroff, and R.S. Lloyd. (2000). Topoisomerase II from
chlorella virus PBCV-1. Characterization of the smallest known type
II topoisomerase. J. Biol. Chem. 275:6915-6921.
Plugge, B., S. Gazzarrini, M. Nelson, R. Cerana, J.L. Van Etten,
C. Derst, D. DiFrancesco, A. Moroni, and G. Thiel. (2000). A potassium
channel protein encoded by chlorella virus PBCV-1. Science 287:1641-1644.
Sun, L., J.R. Gurnon, B.J. Adams, M.V. Graves, and J.L. Van Etten.
(2000). Characterization of a b-1,3-glucanase encoded by chlorella
virus PBCV-1. Virology 276:27-36.
Van Etten, J.L. (2000). Phycodnaviridae. Virus Taxonomy, Classification
and Nomenclature of Viruses, Seventh Report.
M.H.V. Van Regenmortel, C.M. Fauquet, D.H.L. Bishop, E.B.Carstens,
M.K. Estes, S.M. Lemon, J. Maniloff, M.A. Mayo, D.J. McGeoch, C.R.
Pringle, R.B.
Wickner (eds). pp. 183-193. Academic Press, London.
Graves, M.V., C.T. Bernadt, R. Cerny, and J.L. Van Etten. (2001).
Molecular and genetic evidence for a virus-encoded glycosyltransferase
involved in protein glycosylation. Virology 285:332-345.
Zhang, Y., B. Adams, L. Sun, D. Burbank, and J.L. Van Etten. (2001).
Intron conservation in the DNA polymerase gene encoded by chlorella
viruses. Virology 285:313-321.
Fortune, J.M., O.V. Lavrukhin, J.R. Gurnon, J.L. Van Etten, R.S.
Lloyd, and N. Osheroff. (2001). Topoisomerase II from chlorella virus
PBCV-1 has an exceptionally high DNA cleavage activity. J. Biol.
Chem. 276:24401-24408.
Van Etten, J.L. (2001). Genus Chloroviruses (Phycodnaviridae). In:
The Springer Index of Viruses. C. A. Tidona and G. Darai (eds). Pp.
y724-731. Springer-Verlag, Berlin.
Gazzarrini, S., J.L. Van Etten, D. DiFrancesco, G. Thiel, and A.
Moroni. (2002). Voltage independent inhibition of virus encoded miniature
K+-channel Kcv by extracellular Ca2+. J. Membrane Biol. 187: 15-25.
Fortune, J.M., J.S. Dickey, O.V. Lavrukhin, J.L. *Van Etten, R.S.
Lloyd, and N.
Osheroff. 2002. Site-specific DNA cleavage by chlorella virus topoisomerase
II. Biochemistry 41:11761-11769.
Morehead, T., J.R. Gurnon, B. Adams, K.W. Nickerson, L.A. Fitzgerald,
and J.L. Van
Etten. 2002. Ornithine decarboxylase encoded by chlorella virus PBCV-1.
Virology 301:165-175.
Castberg, T., R. Thyrhaug, A. Larsen, R.A. Sandaa, M. Hedal, J.L.
*Van Etten, and G. Bratbak. 2002. Isolation and characterization
of a virus that infects Emiliania huxleyi (Haptophyceae). J. Phycology
38:767-774.
Moroni, A., C. Viscomi, V. Sangiorgio, C. Pagliuca, T. Meckel, F.
Horvath, S.
Gazzarrini, P. Valbuzzi, J.L. *Van Etten, D. DiFrancesco, and G.
Thiel. 2002. The short N-terminus is required for functional expression
of the virus-encoded miniature K+ channel Kcv. FEBS Lett. 530: 65-69.
Nandhagopal, N., A. Simpson, J.R. Gurnon, X. Yan, T. S. Baker, M.V.
Graves, J.L. Van Etten*, and M.G. Rossmann. 2002. The structure and
evolution of the major capsid protein of a large, lipid-containing,
DNA virus. Proc. Natl. Acad. Sci. 99: 14758-14763.
*Van Etten, J.L., M.V. Graves, D.G. Muller, W. Boland, and N. Delaroque.
(2002). Phycodnaviridae - large DNA algal viruses. Arch. Virology
147:1479-1516.
Petrik, D.T., A. Iseli, B.A. Montelone, J.L. *Van Etten, and R.J.
Clem. (2003). Improving baculovirus resistance to UV inactivation:
Increased virulence resulting from expression of a DNA repair enzyme.
J. Invert. Pathology 82: 50-56.
Roberts, R.J., et al. (2003). A nomenclature for restriction enzymes,
DNA methyltransferases, homing endonucleases and their genes. Nucleic
Acids Res. 31. 1805-1812.
Tonetti, M., Zanardi, D., Gurnon, J.R., Fruscione, F., Armirotti,
A., Damonte, G., Sturla, L., De Flora, A. and Van Etten, J.L.. (2003).
Chlorella virus PBCV-1 encodes two enzymes involved in the biosynthesis
of GDP-L-fucose and GDP-D-rhamnose. J. Biol. Chem. 278: 21672-21677.
Mehmel, M., Rothermel, M., Meckel, T., Van Etten, J.L., Moroni,
A., and Thiel, G. (2003). Possible function for virus encoded K+
channel Kcv in the replication of chlorella virus PBCV-1. FEBS Lett.
552: 7-11.
Gazzarrini, S., Severino, M., Lombardi, M., Morandi, M., DiFrancesco,
D., Van Etten, J.L, Thiel, G., and Moroni, A. (2003). The viral potassium
channel Kcv: structural and functional features. FEBS Lett. 552:
12-16.
Kang, M., Moroni, A., Gazzarrini, S., and Van Etten, J.L. (2003).
Are chlorella viruses a rich source of ion channel genes. FEBS Lett.
552: 2-6.
Zhang, Y., Calin-Jageman, I., Gurnon, J.R., Choi, T.-J., Adams,
B., Nicholson, A.W., and Van Etten, J.L. (2003). Characterization
of a chlorella virus PBCV-1 encoded ribonuclease III. Virology. 317:
73-83
Van Etten, J.L. (2003). Unusual life style of giant chlorella
viruses. Annu. Rev. Genetics. 37: 153-195.
Simpson, A.A., N. Nandhagopal,
J.L. Van Etten, and M.G. Rossmann. (2003).
Structural analyses of Phycodnaviridae and Iridoviridae requires
extension of the rules governing quasi-symmetry. Acta Crystallogr.
D59: 2053-2059.
Moroni, A., J.L. Van Etten, and G. Thiel. (2004). Structure and
function of a viral encoded K+ channel. In Viral Membrane Proteins:
Structure, Function, Drug Design. W. Fischer (ed). Kluwer Academic/Plenum
Publishers p. 21-32.
Markine-Goriaynoff, N., L. Gillet, J.L. Van Etten, H. Korres, N.
Verma, and A. Vanderplasschen. (2004). Glycosyltransferases encoded
by viruses. J. Gen Virol. 85: 2741-2754.
Wilson, W. H., J.L. Van Etten, D.S. Schroeder, K. Nagasaki, C. Brussaard,
N. Delaroque,
G. Bratbak, and C. Suttle. (2004). Phycodnaviridae. In: Virus Taxonomy,
VIIIth Report of the ICTV (C.M. Fauquet, M.A. Mayo, J. Maniloff,
U. Desselberger, and L.A. Ball, eds), 163-175. Elsevier/Academic
Press, London.
Kang, M., A. Moroni, S. Gazzarrini, D. DiFrancesco, G. Thiel, M.
Severino, and J.L.
Van Etten. (2004). Small potassium ion channel proteins encoded by
chlorella viruses. Proc. Natl. Acad. Sci. USA 101: 5318-5324.
Gazzarrini, S., M. Kang, J.L. Van Etten, D. DiFrancesco, G. Thiel,
and A. Moron (2004). Long-distance interactions within the potassium
channel pore are revealed by molecular diversity of viral proteins.
J. Biol. Chem. 279,28443-28449.
Kang, M., M. Graves, M. Mehmel, A. Moroni, S. Gazzarrini, G. Thiel,
J.R. Gurnon, and J.L. Van Etten. (2004). Genetic diversity in chlorella
viruses flanking kcv, a gene that encodes a potassium ion channel
protein. Virology 326, 150-159.
Shah, R., C.S. Coleman, K. Mir, J. Baldwin, J.L. Van Etten, N.V.
Grishin, A.E. Pegg, B.A. Stanley, and M.A. Phillips. (2004). Chlorella
virus PBCV-1 encodes an unusual arginine decarboxylase that is a
close homolog of eukaryotic ornithine decarboxylases. J. Biol. Chem.
279, 35760-35767.
Chan, S.H., Z. Zhu, J.L. Van Etten, and S.Y. Xu. (2004). Cloning
of CviPII nicking and
modification system from chlorella virus NYs-1 and application of
Nt.CviPII in random DNA amplification. Nucleic Acids Res. 32, 6187-6199.
Kuznetsov, Y.G., J.R. Gurnon, J.L. Van Etten, and A. McPherson.
(2004). Atomic force microscopy investigation of a chlorella virus,
PBCV-1. J. Struct. Biol. (in press).
Graziani, S., Y. Xia, J.R. Gurnon, J.L. Van Etten, D. Leduc, S.
Skouloubris, H. Myllykallio, and U. Liebl. (2004). Functional analysis
of FAD-dependent thymidylate synthase ThyX from Paramecium bursaria
chlorella virus. J. Biol. Chem. 279, 54340-54347.
Dickey, J.S., T-J. Choi, J.L. Van Etten, and N. Osheroff. (2005).
Chlorella virus Marburg
topoisomerase II: high DNA cleavage activity as a characteristic
of chlorella virus type II enzymes. Biochemistry (in press).
Kang, M., D.D. Dunigan, and J.L. Van Etten. (2005). Chloroviruses:
a genus of Phycodnaviridae that infect certain chlorella-like green
algae. Mol. Plant Path. (in press).
|
