Chemokines and HIV Dementia
Jialin
Zheng, MD - University of Nebraska Medical Center, Center
for Neurovirology and Neurodegenerative Disorders.
The engagement of neuronal chemokine receptors
by progeny HIV-1 and chemokines is investigated exploring its relevance
in HIV-1 neuropathogenesis. The hypothesis proposed is that virion
and/or chemokine binding to chemokine receptors induces activation
of neuronal signaling pathways leading to cell injury and/or repairing.
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