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Herpes Viral Latency and Interferon Regulatory Factors

Luwen Zhang, PhD - University of Nebraska-Lincoln, School of Biological Sciences.

Interferon regulatory factor 7 (IRF-7) plays important roles in viral latency, immune regulation, as well as host defense mechanisms. Epstein-Barr virus (EBV) latency, which is the best available system to study the functions of IRF-7, will be used to examine the role of IRF-7 in virus-cell interactions and transformation.