Our research program addresses pathogenic and therapeutic questions of some the most devastating viral and neuroimmune disorders facing the global community including molecular, epidemiological, and biochemical approaches to address fundamental questions concerning viral replication, latency, assembly and pathogenesis. These projects include the investigation of mechanisms of HIV replication and pathogenesis; and neurodegenerative diseases such as Alzheimer's disease, prion diseases and HIV-1-associated dementia. Other projects involve chronic and latent infections caused by viruses such as herpes simplex, Epstein-Barr and Kaposi's Sarcoma associated herpesvirus. Investigators are also studying viral host interactions including the mechanism of viral induced cellular transformation.
Charles Wood, PhD - University of Nebraska-Lincoln, School of Biological Sciences.
The laboratory focuses on HIV and human herpesvirus, and the roles play by these viruses in immunosuppression and cancer development. One of the ongoing projects is to study the transmission and evolution of HIV and Human Herpesvirus 8 (HHV-8), a virus linked to Kaposi's Sarcoma, a rare cancer often found in AIDS patients. This project is being carried out in Africa where infection by both HIV and HHV-8 is at the epidemic level. Our goal is to understand how these viruses regulate gene expression, replicate, transmit and cause diseases. This will lead to knowledge that can help in the development of strategies to prevent infection and disease development.
News
5-6-2013 - Tiffani Hix was hired as the new Grants Specialist
4/9/2013 - For Yue Tso passed his dissertation and will be graduating his PhD in May.
3-1-2013 - Landon Olp was published in the International Journal of Cancer.. Link..
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