Current Research

    Dr. Dussault’s research interests include:

· Synthesis of peroxide-containing natural products.
· New methods for organic oxidations based upon ozone, singlet oxygen, and hydrogen peroxide.
· Molecular basis for fungal signaling.
· Cutin and related polyester biopolymers.

Recent Key Publications

Peng Dai, Patrick H. Dussault, and Tony K. Trullinger; “Magnesium/Methanol: An Effective Reducing Agent for Peroxides”, J. Org. Chem. 69(8), 2851-2852 (2004).

Roman Shchepin, Jacob M. Hornby, Erin Burger, Timothy Niessen, Patrick H. Dussault, and Kenneth W. Nickerson, “Quorum Sensing in Candida Albicans: Probing Farnesol-Receptor Interactions with 40 Natural and Synthetic Farnesol Analogs” Chemistry and Biology 10, 743-750 (2003).

Aqeel Ahmed, Stephenie Cohen-Gould, Terry Crawford, Y.S. Ha, Monica Hollrah, Farhana Noor-E-Ain, Martin B. Dickman, and Patrick H. Dussault, “Synthesis of (R) - and (S)-10, 16-Dihydroxyhexadecanoic Acid: Cutin Stereochemistry and Fungal Activation”, Phytochemistry, 63, 47-52 (2003).

Patrick H. Dussault, Tony K. Trullinger, and Farhana Noor-E-Ain, “Opening of Substituted Oxetanes with H₂O₂ and Alkyl Hydroperoxides: A Stereoselective Approach to 3-Peroxyalcohols and 1, 2, 4-Trioxepanes”, Organic Letters 4, 4591-4593 (2002).

Recent Graduates and Affiliations

· Tony Trullinger; Ph.D.; NIH postdoc at Univ. of Michigan
· Qiang Han, MS; Graduate student at Penn
· Jeff Schultz, Ph.D.; NIH postdoc at UC Irvine; Arena Pharm. (San Diego)
· Su Cho-Schultz, MS; Scientist, Pfizer, La Jolla, CA
· Bridget Miller, MS; Scientist, Pharmacia-Upjohn
· Todd Eary, Ph.D.; NIH postdoc at Univ. of Texas; Array-Biopharma (CO)
· Don Davies, Ph.D.; Assistant Professor at Weber State Univ. (UT)