The Holding Lab focuses on functional genomics studies of endosperm development in cereals and applied methods for improving kernel quality. Researchers use different methods to understand the molecular genetic basis of endosperm modification in Quality Protein Maize (QPM) and incorporate this knowledge into accelerated QPM breeding projects. A large-scale mutagenesis, mapping and gene identification platform for maize has been developed to enhance general understanding of factors essential for endosperm filling and maturation. The mutant population is also being used to investigate mineral homeostasis in vegetative tissues and seeds through an extensive collection of leaf yellow stripe/seed size mutants. The lab is interested in kernel protein quality and digestibility in sorghum, and a gene editing approach is being used to improve these parameters.
Graduate student mentorship through the following programs:Research Keywords
Functional Genomics, Genome Editing, Maize, Protein Quality, Storage Proteins