You (Joe) Zhou, PhD

University of Nebraska-Lincoln, Center for Biotechnology
E117 Beadle Center
Lincoln, NE 68588-0665
(402)-472-5935 (Office)
(402)-472-5942 (Lab)
Lab Page

Research Professor

  • Advanced fluorescence/confocal/electron microscopy and live-cell imaging analysis at micro/nano scales.

  • Human and animal cell biology/histology/neurobiology.

  • Immunolabeling fluorescence or electron microscopy.

  • Negative staining (viruses, bacteria, exosomes, nanoparticles, and nanofibers) TEM.

  • Ultrastructural TEM and topographic SEM analyses of tissues, cells, nanoscale particles/fibers.



Postdoctoral Fellow (Molecular Cell Biology/Microscopy)
University of Toronto, Toronto, Ontario, Canada


Doctor of Philosophy (Animal Cell Biology)
Department of Zoology, University of Western Ontario, London, Ontario


Bachelor of Science (Major in Animal Histology/Cell Biology)
Department of Biology, Nanchang University (former Jiangxi University),Nanchang, Jiangxi, R.R. China

Professional Experience


Director, Microscopy Research Core Facility
Center for Biotechnology, University of Nebraska-Lincoln, NE.


Courtesy Faculty, School of Biological Sciences
University of Nebraska-Lincoln, NE.


Research Professor, School of Veterinary Medicine & Biomedical Sciences
University of Nebraska-Lincoln, NE.


Research Associate Professor, Department of Veterinary & Biomedical Sciences
University of Nebraska-Lincoln, NE.


Research Assistant Professor, School of Biological Sciences
Department of Veterinary & Biomedical Sciences,University of Nebraska-Lincoln, NE.


Director, Antibody Core Research Facility
Center for Biotechnology, University of Nebraska-Lincoln, NE.


Instructor-Research Faculty, Department of Neurosciences, Pennington
Biomedical Research Center, Louisiana State University, Baton Rouge, LA.

Research Publication

Dasgupta S., Y. Zhou, M. Jana, N.L. Banik and K. Pahan. 2003. Sodium phenylacetate inhibits the adoptive transfer of experimental allergic encephalomyelitis in SJL/J mice at multiple steps. J. Immunol. 170(7):3874-82.
Dasgupta S, M. Jana M, Y. Zhou, Y.K. Fung, S. Ghosh, K. Pahan. 2004 Antineuro-inflammatory effect of NF-kappa-B essential modifier-binding domain peptides in the adoptive transfer model of experimental allergic encephalomyelitis. J. Immunol. 173(2):1344-54.
Liu, Y., Z. Liu, H. Gao, Y. Zhou, E. J. Androphy and J. J. Chen. 2005 Opposing Effects of Bovine Papillomavirus Type 1 E6 and E7 Genes on Fas-Mediated Apoptosis. Oncogene 24(24):3942-53
Xu, D. A. Buehner, J. Xu, T. Lambert, C. Nekl, M.K. Nielsen, Y. Zhou. 2006. A polymorphic glucocorticoid receptor in a mouse population may explain inherited altered stress response and increased anxiety-type behaviors. FASEB J Nov 20(13): E1802–E1810.
Peng H, Whitney N, Wu Y, Tian C, Dou H, Zhou Y, Zheng J. 2008. HIV-1-infected and/or immune-activated macrophage-secreted TNF-alpha affects human fetal cortical neural progenitor cell proliferation and differentiation. Glia. 2008 Jun; 56(8):903-16.
Kehr S, Malinouski M, Finney L, Vogt S, Labunskyy VM, Kasaikina MV, Carlson BA, Zhou Y, Hatfield DL, Gladyshev VN. 2009. X-Ray Fluorescence Microscopy Reveals the Role of Selenium in Spermatogenesis. J Mol Biol. 2009 Jun 26; 389 (5):808-18.
Rodriguez-Rocha H, Garcia-Garcia A, Pickett C, Sumin L, Jones J, Chen H, Webb B, Choi J, Zhou Y, Zimmerman MC, Franco R. 2013. Compartmentalized oxidative stress in dopaminergic cell death induced by pesticides and complex I inhibitors: Distinct roles of superoxide anion and superoxide dismutases. Free Radic Biol Med. 2013 Apr 19. pii: S0891-5849(13)00161-5. 2013.04.021.
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Courses Taught

Life 491/891

Lecture and demos for “Advanced Microscopy” in “Introduction to Core Facilities of Center for Biotechnology”
(Spring semester)

Bios 111
Bios 314

Show & tell sessions for “Introduction to advanced microscopy”
(Spring & Fall semester)

Bio 110
(Doane University)

"Inquiry Laboratory: Introduction to Biological Investigation" TEM analysis of bacteriophages

BIO 190
(Nebraska Wesleyan University)

"BIO 1400: Intro. Bio. Inquiry": TEM analysis of bacteriophages

Bios 136
(University of Nebraska- Lincoln)

"Discovery Research: Virus Hunting": TEM analysis of bacteriophages